Refine your search
Collections
Co-Authors
Journals
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Vora, A.
- Clinical Study of Hypertension in Young Adults
Abstract Views :211 |
PDF Views:0
Authors
Affiliations
1 Department of Medicine, Bharati Vidyapeeth Deemed University, Medical College and Bharati Hospital, Pune, 411002, IN
2 Department of Medicine, Bharati Vidyapeeth Deemed University, Medical College and Bharati Hospital, Pune, IN
1 Department of Medicine, Bharati Vidyapeeth Deemed University, Medical College and Bharati Hospital, Pune, 411002, IN
2 Department of Medicine, Bharati Vidyapeeth Deemed University, Medical College and Bharati Hospital, Pune, IN
Source
The Indian Practitioner, Vol 69, No 4 (2016), Pagination: 28-32Abstract
This prospective study was undertaken in 40 patients of hypertension in the age group of 18 - 40 years, randomly selected from the in and outdoor patient department over a period of two years. The aim was to study the clinical profile, associated risk factors, assess the target organ damage and identify the causes of hypertension in young adults.In conclusion a definite male preponderance with a male to female ratio of 1.35:1, especially stage II hypertension. 77.5% patients showed target organ damage in the present study (Hypertensive retinopathy), incidence of LVH was seen in 40%. The commonest cause of secondary hypertension observed was renal parenchymal disease (44.44%). The relative possibility of the hypertension being secondary was increased, which had a distinct possibility of cure.
Keywords
Secondary Hypertension, Young Adults, Risk Factors, Target Organ Damage.- Valproate Causing Recurrent Acute Pancreatitis
Abstract Views :217 |
PDF Views:3
Authors
Affiliations
1 Dept. of Medicine, Bharati Vidyapeeth Deemed University Medical College and Hospital, Pune, Maharashtra, IN
2 Dept, of Medicine, Bharati Vidyapeeth Deemed University Medical College and Hospital, Pune, Maharashtra, IN
1 Dept. of Medicine, Bharati Vidyapeeth Deemed University Medical College and Hospital, Pune, Maharashtra, IN
2 Dept, of Medicine, Bharati Vidyapeeth Deemed University Medical College and Hospital, Pune, Maharashtra, IN
Source
The Indian Practitioner, Vol 70, No 8 (2017), Pagination: 36-38Abstract
Valproic acid is used either as monotherapy or in combination with other anticonvulsants for the treatment of simple, mixed and complex partial seizures, myoclonic seizure, generalised tonic- clonic seizure, acute manic episodes in bipolar disorder, and for prophylaxis of migraine headaches. The association of sodium valproate and pancreatitis is sometimes referred to as idiosyncratic as pancreatitis can develop after 1 week to 8 years of exposure to sodium valproate. We report a case of 39 year old male known case of seizure disorder presenting with recurrent episodes of epigatrium and right hypochondrium abdominal pain associated with vomiting over a period of 4 years. After excluding other causes of pancreatitis, a diagnosis of valproate induced necrotising pancreatitis was established.Keywords
Valproic Acid, Pancreatitis.References
- Pancreatitis associated with valproic acid: a review of the literature. Chapman SA, Wacksman GP, Patterson BD. Pharmacotherapy. 2001;21:1549– 1560.
- Idiosyncratic adverse reactions to antiepileptic drugs. Zaccara G, Franciotta D, Perucca E. Epilepsia.2007;48:1223–1244.
- Gerstner T, Büsing D, Bell N. et al. Valproic acidinduced pancreatitis:16 new cases and a review of the literature. J Gastroenterol. 2007;42(1):39–48.
- Wilmink T, Frick WK. Drug induced pancreatitis. Drug safety 1996; 14: 406-423.
- Pancreatitis associated with valproic acid therapy. Batalden PB, Van Dyne BJ, Cloyd J. Pediatrics.1979;64:520–522.
- Pancreatitis due to valproic acid. Camfield PR, Bagnell P, Camfield CS, Tibbles JA. Lancet. 1979;1:1198–1199.
- Hamad AE, Fawzi ME. Valproate associated acute pancreatitis. Neurosciences. 2000;5(3):156–8.
- The role of oxygen-derived free radicals in the pathogenesis of acute pancreatitis. Sanfey H, Bulkley GB, Cameron JL. Ann Surg. 1984;200:405– 413.
- Acute pancreatitis coincident with valproate use: a critical review. Pellock JM, Wilder BJ, Deaton R, Sommerville KW. Epilepsia. 2002;43:1421–1424.
- Carnitine levels in valproic acid-treated psychiatric patients: a cross-sectional study. Moreno FA, Macey H, Schreiber B. J Clin Psychiatry. 2005;66:555–558.
- The spectrum of valproic acid-associated pancreatitis. Werlin SL, Fish DL. Pediatrics. 2006;118:1660– 1663.